Porcine dynorphin A(1-13)
CAS No. 72957-38-1
Porcine dynorphin A(1-13) ( Dynorphin A Porcine Fragment 1-13 )
产品货号. M29878 CAS No. 72957-38-1
Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1066 | 有现货 |
|
10MG | ¥1685 | 有现货 |
|
25MG | ¥3499 | 有现货 |
|
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
5MG | ¥1066 | 有现货 |
|
10MG | ¥1685 | 有现货 |
|
25MG | ¥3499 | 有现货 |
|
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称Porcine dynorphin A(1-13)
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.
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产品描述Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.(In Vivo):Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time.
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同义词Dynorphin A Porcine Fragment 1-13
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通路Others
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靶点Other Targets
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受体Κ opioid receptor
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研究领域——
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适应症——
化学信息
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CAS Number72957-38-1
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分子量1604
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分子式C75H126N24O15
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纯度>98% (HPLC)
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溶解度H2O : ≥ 60 mg/mL (37.41 mM)
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SMILES——
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化学全称Sequence:Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75.
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