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Porcine dynorphin A(1-13)

CAS No. 72957-38-1

Porcine dynorphin A(1-13) ( Dynorphin A Porcine Fragment 1-13 )

产品货号. M29878 CAS No. 72957-38-1

Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1066 有现货
10MG ¥1685 有现货
25MG ¥3499 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
5MG ¥1066 有现货
10MG ¥1685 有现货
25MG ¥3499 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货

生物学信息

  • 产品名称
    Porcine dynorphin A(1-13)
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.
  • 产品描述
    Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.(In Vivo):Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time.
  • 同义词
    Dynorphin A Porcine Fragment 1-13
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Κ opioid receptor
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    72957-38-1
  • 分子量
    1604
  • 分子式
    C75H126N24O15
  • 纯度
    >98% (HPLC)
  • 溶解度
    H2O : ≥ 60 mg/mL (37.41 mM)
  • SMILES
    ——
  • 化学全称
    Sequence:Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75.
产品手册
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